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SMND-309 activates Nrf2 signaling to alleviate acetaminophen-induced hepatotoxicity and oxidative stress.

PLoS One · 2025 · PMC11957308 · PMID 40163430

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an increasing trendno p-value reported
In addition, SOD, CAT and GSH contents in HepG2 cells were found to be decreased after blocking the Nrf2 pathway, with MDA levels, however, showing an increasing trend ( Fig 8D ).

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