Bile acid is a responsible host factor for high-fat diet-induced gut microbiota alterations in rats: proof of the "bile acid hypothesis".

Biosci Microbiota Food Health · 2025 · PMC11957759 · PMID 40171388

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At week 8, the levels of CA, 7-oxo-DCA, and ursocholic acid increased significantly in the HFD groups, with a notable trend of increase observed for β-MCA, ω-MCA, and DCA ( Fig. 1B ).

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