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Extrachromosomal circular DNA as a novel biomarker for the progression of colorectal cancer.

Mol Med · 2025 · PMC11960012 · PMID 40165080

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an increasing trendno p-value reported
It has a high incidence and mortality rate and has shown an increasing trend in recent years (Siegel et al. 2023 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.