From Edmonton to Lantidra and beyond: immunoengineering islet transplantation to cure type 1 diabetes.

Front Transplant · 2025 · PMC11965681 · PMID 40182604

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failed to reach significanceno p-value reported

Local immunomodulation by FK506 loaded microspheres was necessary as administration of the islets on one flank and the loaded microspheres to another flank of the mice failed to reach significance compared to the control group ( 68 ).

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