Barely Significant
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The PKM2 activator TEPP-46 suppresses cellular senescence in hydrogen peroxide-induced proximal tubular cells and kidney fibrosis in CD-1<sup>db/db</sup> mice.

J Diabetes Investig · 2025 · PMC11970295 · PMID 39840670

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not yet significantno p-value reported
The plasma IL‐6 levels tended to decrease but were not yet significant in the CD‐1 db/db mice treated with TEPP‐46 (Figure 5g ).

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