Injectable hydrogel with miR-222-engineered extracellular vesicles ameliorates myocardial ischemic reperfusion injury via mechanotransduction.

Cell Rep Med · 2025 · PMC11970392 · PMID 40037358

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Consistent with the Tunel results, the ratios of Bax/Bcl2 and cleaved caspase-3/caspase-3 exhibited a decreasing trend in both the TeEV and GEL-TeEV groups ( Figure 4 G), reflecting significant alleviation of myocardial AIRI.

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