A Systematic Targeted Genetic Screen Identifies Proteins Involved in Cytoadherence of the Malaria Parasite P. falciparum.

Erythrocytes infected with CS2_1600 glmS showed no significant decrease in surface fluorescence when treated with GlcN (Figure 7b ); however, erythrocytes infected with CS2_0300 glmS (Figure 7a ) showed a highly significant reduction in the surface detection of PfEMP1 var2csa . 3 Discussion Despite initial skepticism, it is now accepted that malaria parasites export a large number of proteins to their host cell and that these proteins are involved in a number of processes that may be essential for parasite survival either in vitro or in vivo.

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