In MLMs of increasing complexity (Table 2 ), a 10 ml/min/1.73 m 2 decrease in eGFR over the 3-year follow-up period was associated with a highly significant reduction in the summary measures of QoL, i.e. the PCS and the MCS scores independently of an extensive series of potential confounders (all variables listed in Table 1 , see Methods, Statistical Analysis), including the socio-economic status and the corresponding baseline values of PCS and MCS of QoL.
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Quality of life and kidney function in CKD patients: a longitudinal study.
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