Global burden of polycystic ovary syndrome among women of childbearing age, 1990-2021: a systematic analysis using the global burden of disease study 2021.

Concurrently, the prevalence rates of PCOS among WCBA exhibited an increasing trend globally, with an EAPC of 0.77 (0.74–0.81; Figure 1B ).

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However, in the high SDI region, a decreasing trend was observed for prevalence, incidence, and DALYs rates in the 45–49 age group, with an EAPC of −0.02 (−0.22 to 0.18), −0.32 (−0.47 to −0.17), and − 0.02 (−0.22 to 0.17) respectively ( Figure 4D ; Supplementary Figures S11 , S12 ).

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