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Incidence, prevalence, and mortality of localized scleroderma in Quebec, Canada: a population-based study.

Lancet Reg Health Am · 2025 · PMC11979410 · PMID 40206390

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an increasing trendno p-value reported
Over the study period, females had an increasing trend in prevalence (average annual percent change 3.7 [95% CI 3.4–4.2]%) with a peak of 47.1/100,000 [95% CI 44.7–49.1] in 2017, whereas males had a relatively stable prevalence (average annual percent change 0.4 [95% CI −0.04 to 0.9]%) over the study period ( Fig. 3 ).

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