Hierarchical joint analysis of marginal summary statistics-Part I: Multipopulation fine mapping and credible set construction.

Genet Epidemiol · 2024 · PMC11980956 · PMID 38606643

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marginal significanceno p-value reported

Despite mJAM-SuSiE’s outstanding performance under high LD scenarios with moderate causal effect size, we noticed that its results were very sensitive to the marginal significance of the true causal SNPs.

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marginally significantno p-value reported

Many of the marginally significant variants in this region are upstream or intronic of the MMP7 and MMP20 genes.

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