The gas trapped in the amorphous silica particles during their formation process and for the ones with encapsulated drug may be significant in comparison to the m-SiO 2 particles which have an organised large porous network (average pore size 2.7 nm) where adsorbed gas or drug can leak uncontrollably.
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Non-porous silica nanoparticles as a cavitation sensitive vehicle for antibiotic delivery.
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