Longitudinal cellular and humoral immune responses following COVID-19 BNT162b2-mRNA-based booster vaccination of craft and manual workers in Qatar.

Front Immunol · 2025 · PMC11983602 · PMID 40213554

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hedged sentence

0.0600

closest p · 1.2× alpha

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boldest claim

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borderline significantp=0.06so close (0.05 < p ≤ 0.1)

Following booster vaccination, we found a borderline significant (p=0.06) increase in anti-spike granzyme B responses, in particular anti-S1, in infection-naïve participants (S1 – M3 versus M6) ( Figure 3A ).

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