Ablation of Hepatic Asah1 Gene Disrupts Hepatic Lipid Homeostasis and Promotes Fibrotic Nonalcoholic Steatohepatitis in Mice.

P < 0.05 was considered as statistically significant, while P < 0.01 was considered as highly significant.

also in 132,142 other papers

The mRNA levels of SREBF1 and fatty acid saturation-related gene fatty acid synthase 1 (FASN1) in the liver were also significantly increased by Asah1 gene deficiency, whereas the expression of stearoyl-CoA desaturase (SCD) and fatty acid desaturase (FADS) exhibited an increasing trend, but was not statistically significant ( Figure 5 K).

also in 63,971 other papers