Human Pituitary Organoids: Transcriptional Landscape Deciphered by scRNA-Seq and Stereo-Seq, with Insights into SOX3's Role in Pituitary Development.

Functional tests for ACTH secretion conducted on organoids between days 100–150 yielded positive results for the low glucose test, the CRH stimulation test, and the dexamethasone suppression test, while the DDAVP test showed an increasing trend albeit being negative (Figure 3C–F ).

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