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Re-Evaluating Acceptable Intake: A Comparative Study of N-Nitrosomorpholine and N-Nitroso Reboxetine Potency.

Environ Mol Mutagen · 2025 · PMC11986803 · PMID 40119631

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a decreasing trendno p-value reported
Despite dose‐related increases in the total counts of T>C transitions, their proportion showed a decreasing trend due to more significant increases in other mutation subtypes (i.e., T>A, T>C, and T>G).

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an increasing trendno p-value reported
To test for an increasing trend across dose groups and for an overall test effect, a one‐way analysis of variance (ANOVA) on all groups was conducted, with two‐sided trend tests on vehicle control and test article‐treated groups and two‐sided pairwise comparisons of each group to the vehicle control group.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.