Brain Volume Measures in Adults with MOG-Antibody-Associated Disease: A Longitudinal Multicenter Study.

The post hoc analysis revealed a significant difference between MS and MOGAD cohorts (mean difference −81.73 cm 3 , p = 0.012), and a borderline significant difference was noted between MS and HC groups (mean difference −71.4 cm 3 , p = 0.045) ( Figure 3 B).

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These results are partly consistent with a previous preliminary analysis [ 21 ] from our group, where it was observed that the mean PBVC/y was lower in MOGAD patients than in RRMS patients in a subgroup of patients aged <60 years and with a disease duration of ≤10 years, with borderline significance.

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