Though not significant, an increasing trend was observed for PTV exposure across OATP1B1 increased, normal, decreased, and poor function phenotype in ESRD patients, while larger RSV exposure was observed in BCRP poor function phenotype in both HVs and ESRD patients ( Figures S8 and S9 ).
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Microdose Cocktail Study Reveals the Activity and Key Influencing Factors of OATP1B, P-Gp, BCRP, and CYP3A in End-Stage Renal Disease Patients.
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