Shigella phages, like all other bacteriophages, have a limited host range, infecting just certain strains of Shigella, whilst others have a broader host spectrum and these host specificity differences are shaped by the development of important genomic characteristics that govern phage-host interactions, such as the proteins involved in host recognition and genome injection, so comparative genomic studies of Shigella phages are thus critical for discovering conserved genetic components that may be significant for phage infectivity, as well as understanding the processes that contribute to phage population diversity [ 22 ].
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