highly significantP < 0.001
Administration of DXP with 500 mg/kg 5-FU resulted in a highly significant decrease in uric acid levels ( P < 0.001) and a significant decrease in BUN and creatinine levels ( P < 0.05).
Administration of DXP with 500 mg/kg 5-FU resulted in a highly significant decrease in uric acid levels ( P < 0.001) and a significant decrease in BUN and creatinine levels ( P < 0.05).
Administration of DXP at 500 mg/kg and 1000 mg/kg decreased the rate of weight loss in the 5-FU+DXP500 and 5-FU+DXP1000 groups even turning the curves into a positive trend at the end of the test.