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Molecular landscape of clear cell renal cell carcinoma: targeting the Wnt/β-catenin signaling pathway.

Discov Oncol · 2025 · PMC11996749 · PMID 40227498

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a notable trendno p-value reported
In ccRCC, there is a notable trend toward reduced SFRP1 expression, with promoter hypermethylation emerging as the primary mechanism responsible for silencing the SFRP1 gene.

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