Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway.

Front Pharmacol · 2025 · PMC11996808 · PMID 40235530

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a decreasing trendno p-value reported

Additionally, GAH mice showed significantly decreased liver weight and liver/body ratio compared to the HFHC group, whereas GAL mice only showed a decreasing trend in the liver/body ratio ( Figure 1G, H ), indicating that GA reduces fatty liver in a dose-dependent manner.

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