Global, regional and national trends in the epidemiology of rheumatoid arthritis from 1990 to 2021: an age-period-cohort effect analysis of the global burden of disease study 2021.

However, all SDI regions, except for low SDI region, saw a decreasing trend of risk on RA mortality, with net drifts ranging from −2.570% (95% CI −3.035 to −2.103) in high SDI region to −0.691% (95% CI −1.075 to −0.305) in low-middle SDI region ( table 1 ; online supplemental tables S7–S9 ).

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