Trimetazidine effect on kidney function in patients undergoing coronary procedures.

All Standardized Mean Differences (SMDs) were either below or very close to 0.1.CIN rates at 72 h were lower in Group I (13.2%) than Group II (22.0%; unadjusted p = 0.019, Bonferroni-adjusted p = 0.352, FDR-adjusted p = 0.047), suggesting a modest protective effect of TMZ that weakens under stringent correction but remains borderline significant with FDR.

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A negative correlation between TMZ’s effect and contrast volume ( R = -0.187, unadjusted p = 0.007, Bonferroni-adjusted p = 0.056, FDR-adjusted p = 0.017) hinted at dose-independent protection, retaining borderline significance with FDR.

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