Barely Significant
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Oral microbiome profiles in oral potentially malignant disorders and oral cancer - A diagnostic perspective.

J Oral Maxillofac Pathol · 2025 · PMC12002586 · PMID 40248614

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a decreasing trendno p-value reported
Firmicutes showed a decreasing trend in leukoplakia and OSMF and a significant decrease in OSCC (32.17%) compared to normal (43.94%), P value < 0.01.

also in 25,969 other papers

an increasing trendno p-value reported
An increase in relative abundance of Gram-negative bacteria as well as an increasing trend in the abundance of periodontal taxa was observed in OSCC.

also in 31,969 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.