Despite the significant heterogeneity, the results remain statistically robust with a highly significant p -value, reinforcing the strength of the observed effect. 3.3.4 Improvement of ≥1 Class in NYHA Improvement of ≥1 Class in NYHA was reported in Four studies ( N = 231 patients) [ 11 , 12 , 20 , 21 ].
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Efficacy of aficamten in obstructive hypertrophic cardiomyopathy: A systematic review and meta-analysis.
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