Marker selection strategies for circulating tumor DNA guided by phylogenetic inference.

Bioinformatics · 2025 · PMC12002908 · PMID 40163695

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an overall trendno p-value reported

Our method is able to use just a small subset of markers to capture an overall trend of gradual and then accelerating expansion of several subclones after surgery indicative of relapse.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.