Production optimization of a thermostable alkaline and detergent biocompatible protease by Bacillus paramycoides WSA for the green detergent industry.

All tested factors exhibited a highly significant effect on protease activity, specifically in terms of their quadratic dependence, with p-values ranging from 0.001 to 0.002 ( p < 0.01), i.e., not all factors influence the response linearly nor through interactions, since all coefficients of linear terms and all interactions present a meager value (Table 3 ).

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