Transcriptomic analysis of benznidazole-resistant Trypanosoma cruzi clone reveals nitroreductase I-independent resistance mechanisms.

PLoS One · 2025 · PMC12005674 · PMID 39964998

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a decreasing trendno p-value reported

In the first case, genes such as retrotransposon hot spot (RHS) protein, trans-sialidases, mucins, MASP, and dispersed gene family protein 1 (DGF-1) were found in the resistant clone with a decreasing trend in the number of transcripts.

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