Network Pharmacology and Experimental Validation of the Effects of Shenling Baizhu San, Quzhi Ruangan Fang and Gexia Zhuyu Tang on the Intestinal Flora of Rats with NAFLD.

SLBZS and QZRGF groups ( Figure 8C ) Compared with the Normal group, the Shannon index of the intestinal contents of the rats in the Model group was reduced, and the GXZYT, QZRGF, SLBZS and Fenofibrate groups showed an increasing trend, and the most significant improvement in the flora was observed in the SLBZS group followed by the QZRGF and GXZYT groups among the 8-week groups.

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Through our study we also found that each group of Bacteroidetes, Firmicutes had the highest percentage of genera, and the level of Firmicutes showed a decreasing trend and the Bacteroidetes showed an increasing trend after the intervention of NAFLD rats by QZRGF, GXZYT and SLBZS.

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