Given that MHC class II on epithelial cells is key to airway T RM cell biology, the polymorphisms in MHC class II-related genes that have been linked with adult-onset asthma 107 , 108 may be significant for influencing the relative frequencies and activities of CD4 + T RM cell lineages in the airways.
← all excerpts
Lung CD4<sup>+</sup> resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease.
1
—
—