Over-the-Counter Ibuprofen-Induced Pre-Pyloric Gastric Perforation in a 28-Month-Old Child: A Rare Pediatric Case.

Cureus · 2025 · PMC12015679 · PMID 40271233

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Additionally, recent pediatric data underscore an increasing trend in NSAID-related gastropathy, with some investigations reporting a higher risk of peptic ulceration and perforation in children who use over-the-counter analgesics without medical supervision [ 8 ].

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