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Slit-Robo signaling supports motor neuron avoidance of the spinal cord midline through DCC antagonism and other mechanisms.

Front Cell Dev Biol · 2025 · PMC12018395 · PMID 40276653

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Slit2, on the other hand, appeared to repel motor axons at peak concentrations of 100 ng/mL and above, although this effect did not quite reach statistical significance ( Figures 5C, D ).

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