Single-cell sequencing reveals intracranial microvasculature-derived CXCL12 promotes CD8<sup>+</sup> T-cell infiltration and blood-brain barrier dysfunction after subarachnoid hemorrhage in mice.

J Neuroinflammation · 2025 · PMC12020083 · PMID 40270006

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an increasing trendno p-value reported

We observed an increasing trend of CXCL12 in the brain cortex after SAH, and both endothelial cells and pericytes presented high expression levels of CXCL12.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Single-cell sequencing reveals intracranial microvasculature-derived CXCL12 promotes CD8&lt;sup&gt;+&lt;/sup&gt; T-cell infiltration and blood-brain barrier dysfunction after subarachnoid hemorrhage in mice.

The sentences

Single-cell sequencing reveals intracranial microvasculature-derived CXCL12 promotes CD8<sup>+</sup> T-cell infiltration and blood-brain barrier dysfunction after subarachnoid hemorrhage in mice.