highly significantp = 0.031
The expression of VEGF was absent in 4 (14.8%), weak in 16 (59.3%), mild in 4 (14.8%), and strong in 3 (11.1%) cases ( Table 2 ). The chi-square test revealed a highly significant difference in the expression of HIF-1α and VEGF between radicular cysts and periapical granulomas (chi-square test = 8.906, p = 0.031; chi-square test = 10.401, p = 0.015, respectively).