Evaluation of Lytic and Persistent Human Adenovirus Infections in Tonsil Tissue of Children With Tonsillar Hypertrophy: A Matched Case-Control Study.

However, no HAdV genome was detected in the control group using highly sensitive techniques such as nested PCR and real‐time PCR, resulting in a borderline significant difference between the case and control groups ( p = 0.056) (Table 1 ). 3.3 HAdV ‐C and B Viral Load in Tonsil Tissue Specimens and Throat Swab Samples The in‐house real‐time PCR determined the viral load in tonsil tissues from HAdV‐C positive children with tonsillar hypertrophy, ranging between 4 × 10 3 and 1.9 × 10 6 copies/g with median of 2.6 × 10 4 copies/g.

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