Barely Significant
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The Oxidative Stress of Human Sperm Cryopreservation.

Antioxidants (Basel) · 2025 · PMC12024095 · PMID 40298642

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highly significantno p-value reported
However, this practice has been questioned recently, with density gradient centrifugation (DGC) preparation of semen prior to rate-controlled slow freezing having been shown to yield a highly significant increase in the total number of viable, progressively motile spermatozoa following thawing [ 69 ].

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