Associations between phthalate metabolites and two novel systemic inflammatory indexes: a cross-sectional analysis of NHANES data.

Ann Med · 2025 · PMC12024508 · PMID 40272105

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an increasing trendno p-value reported

From the overall trend, the levels of SII/SIRI showed an increasing trend when the concentration of the mPAEs increased ( Figure 7 ).

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a positive trendno p-value reported

In this study, the outcomes of two mixed exposure models, the WQS model and the BKMR model, indicated an overall positive association between mPAEs and SII/SIRI, demonstrating a positive trend in the collective impact of metabolites on inflammation.

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