Nonlinear Dynamics of TNFR1 and TNFR2 Expression on Immune Cells: Genetic and Age-Related Aspects of Inflamm-Aging Mechanisms.

Polynomial approximation functions were applied to each association using Tukey’s method of bends, allowing for the identification and validation of inflection points where an increasing trend transitions to a decreasing one (or vice versa) ( Figure 5 ).

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