Adjuvant Metronomic Chemotherapy After Surgery in pT1-T2 N0 M0 HER2-Positive and ER/PR-Positive Breast Cancer Plus Targeted Therapy, Anti-Hormonal Therapy, and Radiotherapy, with or Without Immunotherapy: A New Operational Proposal.

However, by doing so, even the healthy, fast-dividing cells of the body are affected, e.g., bone marrow cells, epithelial cells in the gastrointestinal tract, and hair stem cells, causing more or less significant side effects such as cytopenia, nausea, vomiting, diarrhea, and hair loss; a break in treatment is therefore necessary to allow these normal cells to recover [ 1 , 2 , 3 , 4 , 5 ].

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