Barely Significant
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Prognostic significance of KRAS, NRAS, BRAF, and PIK3CA mutations in stage II/III colorectal cancer: A retrospective study and meta-analysis.

PLoS One · 2025 · PMC12027030 · PMID 40279317

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hedged sentence
0.0460
closest p · 0.9× alpha
0.0460
boldest claim

The sentences

marginal significanceP = 0.046actually significant
PIK3CA mutation was associated with favorable DFS at marginal significance (HR = 0.86, 95%CI: 0.75-1.00, P = 0.046, S2 Fig ).

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