Steric Effects of <i>N</i>-Alkyl Group on the Base-Induced Nitrogen to Carbon Rearrangement of Orthogonally Protected <i>N</i>-Alkyl Arylsulphonamides.

Molecules · 2025 · PMC12029463 · PMID 40333883

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

One immediate and highly significant implication of this finding is that it would be advisable to migrate the CO 2 C(CH 3 ) 3 group in the first rearrangement, followed by either CO 2 CH 3 or CO 2 C 2 H 5 in the second rearrangement, if it is desired to prepare an N -methyl or N -ethyl saccharin corresponding to 18 , Scheme 5 .

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Steric Effects of &lt;i&gt;N&lt;/i&gt;-Alkyl Group on the Base-Induced Nitrogen to Carbon Rearrangement of Orthogonally Protected &lt;i&gt;N&lt;/i&gt;-Alkyl Arylsulphonamides.

The sentences

Steric Effects of <i>N</i>-Alkyl Group on the Base-Induced Nitrogen to Carbon Rearrangement of Orthogonally Protected <i>N</i>-Alkyl Arylsulphonamides.