Physiologically-Based Biopharmaceutics Modeling for Ibuprofen: Identifying Key Formulation Parameter and Virtual Bioequivalence Assessment.

Pharmaceutics · 2025 · PMC12030207 · PMID 40284404

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a slight trendno p-value reported

A slight trend of over-prediction of BSV and WSV is also observed. 3.2.

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a decreasing trendno p-value reported

For example, when n = 12, the success rate is approximately 20% for all scenarios, whilst for n = 24 a decreasing trend when increasing the number of trial replicates per run (10 × 10 vs. 4 × 25 vs. 2 × 50) was observed.

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