Cyclooxygenase-2/Prostaglandin E2 Pathway Facilitates Infectious Bronchitis Virus-Induced Necroptosis in Chicken Macrophages, a Caspase-Independent Cell Death.

A 50% serum reduction (9% serum) significantly elevated viral genome load ( p = 0.03), and a 25% media reduction (4.5% serum) resulted in a highly significant increase ( p < 0.0001), with no significant change to serum-free conditions ( p > 0.9) ( Figure 1 B).

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