Iron-Dependent JMJD1A-Mediated Demethylation of H3K9me2 Regulates Gene Expression During Adipogenesis in a Spatial Genome Organization-Dependent Manner.

Genes Cells · 2025 · PMC12035669 · PMID 40289791

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a pronounced trendno p-value reported

Cluster A1, encompassing 7487 TSSs, showed a pronounced trend toward H3K9me2 demethylation by JMJD1A(WT) in JMJD1A‐KD cells, but not by expression of the iron‐coordination‐site defective mutant JMJD1A(H1122A) in JMJD1A‐KD cells (Figure 3E , top panel).

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highly significantno p-value reported

* p < 0.05 was considered statistically significant, while *** p < 0.005 indicated a highly significant difference.

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