Likewise, AMFR protein level showed an obvious trend of reduction during aging, and the 8-month-old APP/PS1 mice exhibited a significant decrease compared to the age-matched WT mice, which indicated a potential role of AMFR in AD progression (Fig. 1 B).
← all excerpts
The autocrine motility factor receptor delays the pathological progression of Alzheimer's disease via regulating the ubiquitination-mediated degradation of APP.
1
—
—