Integrated multi-omics to elucidate the interplay between rumen microorganisms and host metabolism in Hu sheep supplemented with herbal preparations.

Conversely, nucleotides and their derivatives, choline, tryptophan, as well as hormones and hormone-related substances exhibited an increasing trend ( Fig. 8C and F ).

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The findings revealed a decreasing trend in carbohydrates and their metabolites, fatty acyls, bile acids, alcohols, amines, and benzene derivatives in the T1 and T2 groups compared to the Con ( Fig. 8B, D, and F ).

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