Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

Herein, we showed that for both the widely utilized and standardized ACLT + MMx and ACLT rat models of surgically induced OA knee pain, hindlimb static weight-bearing asymmetry is a long-lasting, reproducible and highly significant pain behavioral parameter, particularly in the advanced stages of these models in the period 20–40 weeks post-model induction.

also in 132,142 other papers