Even despite specific estimation of the associations, an increasing trend of circulating PAI-1 levels towards the classes of hepatic steatosis severity has been observed also in younger individuals with overweight or obesity, posing real challenges in terms of cardiovascular risk at every age in apparently healthy individuals with overweight or obesity [ 48 ].
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Liver steatosis is positively associated with plasminogen activator inhibitor-1 in apparently healthy individuals with overweight and obesity: A FibroScan-Based Cross-Sectional study.
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