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Target-Mediated Modeling of Alirocumab in Adolescents and Children ≥8 to <12 Years of Age Using Phase II and III Data.

Clin Pharmacol Drug Dev · 2025 · PMC12044327 · PMID 40136083

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a statistical trendno p-value reported
When HDS was used as a covariate of R 0 in addition to the covariate of k syn , it was a statistical trend, and as a result this potentially important covariate did not remain in the model.

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